Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | TMPRSS15 | P98073 | 8/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042058 | 1.00 | HRH3 (0.55) | HRH3TMPRSS15CRBNABCC2HDAC3 | |
| SCHEMBL22042057 | 0.86 | ABCC2 (0.46) | TMPRSS15ABCC2 | |
| SCHEMBL22042056 | 0.86 | ABCC2 (0.46) | TMPRSS15ABCC2 | |
| SCHEMBL3281502 | 0.83 | HRH3 (0.59) | HRH3TMPRSS15CRBNHDAC3HDAC4 | |
| SCHEMBL13248235 | 0.82 | HRH3 (0.51) | HRH3TMPRSS15CRBNABCC2HDAC3 | |
| Hydrochloric Acid SCHEMBL3107448 | 0.81 | HRH3 (0.50) | HRH3TMPRSS15CRBNABCC2 | |
| Hydrochloric Acid SCHEMBL15121852 | 0.81 | HRH3 (0.50) | HRH3TMPRSS15CRBNABCC2 | |
| SCHEMBL14164261 | 0.80 | HRH3 (0.56) | HRH3TMPRSS15CRBNHDAC3HDAC4 | |
| SCHEMBL20176409 | 0.79 | HRH3 (0.57) | HRH3TMPRSS15CRBNHDAC3HDAC4 | |
| SCHEMBL24183659 | 0.79 | HRH3 (0.69) | HRH3TMPRSS15CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114465-A1 | PREPARATION AND APPLICATION OF HETEROAROMATIC IMINAZOLE COMPOUND | 上海轶诺药业有限公司 | 2020-06-11 | — | — | WO | disclosed |
| US-7754745-B2 | Azacyclopentane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2010-07-13 | — | — | US | disclosed |
| US-20090093527-A1 | Azacyclopentane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | MERCK FROSST CANADA LTD. (CA) | 2009-04-09 | — | — | US | disclosed |
| EP-2032570-A1 | AZACYCLOPENTANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007143824-A1 | AZACYCLOPENTANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093527-A1 | Azacyclopentane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase | SCD, SCD5, SREBF1 | HRH3 4717/4885TMPRSS15 1403/4885CRBN 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.