Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.56 |
| ▸ | WNT3A | P56704 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728190 | 1.00 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL30001736 | 0.94 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL3675566 | 0.94 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL3674099 | 0.92 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL3039881 | 0.90 | HDAC8 (0.56) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL1421021 | 0.90 | SMN1; SMN2 (0.58) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL10788698 | 0.88 | PARP1 (0.63) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL30114977 | 0.88 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL28972842 | 0.88 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL28972845 | 0.88 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142642-B | Preparation method of 1,2, 3-trisubstituted-5-trifluoromethyl pyrrole derivative | 华侨大学 | 2022-03-04 | — | — | CN | claimed |
| CN-117466817-A | Preparation method of polysubstituted pyrazole derivative | 华侨大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-110143935-B | Preparation method of 2, 5-disubstituted furan derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-115093323-A | Beta-functionalized chiral homoallyl alcohol derivative and preparation method and application thereof | 武汉大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-112142642-B | Preparation method of 1,2, 3-trisubstituted-5-trifluoromethyl pyrrole derivative | 华侨大学 | 2022-03-04 | — | — | CN | disclosed |