SCHEMBL3674099

SCHEMBL3674099

Cc1ccc(C(=O)CC(=O)c2cccc(C)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.72
KMT2A Q03164 6/20 0.72
RAB9A P51151 5/20 0.72
NPC1 O15118 4/20 0.72
MAPT P10636 6/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
KDM4E B2RXH2 5/20 0.57
HPGD P15428 5/20 0.57
HTT P42858 4/20 0.57
NPSR1 Q6W5P4 3/20 0.57
LMNA P02545 3/20 0.57
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CTNNB1 P35222 3/20 0.54
WNT3A P56704 3/20 0.54
KCNH2 Q12809 3/20 0.54
TSHR P16473 1/20 0.54
HSD17B10 Q99714 1/20 0.54
PARP1 P09874 1/20 0.53
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728190 0.92 MEN1 (0.64) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL29456641 0.92 MEN1 (0.64) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL30001736 0.91 MEN1 (0.69) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL3675566 0.91 MEN1 (0.69) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL28972845 0.84 MEN1 (0.61) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL30114977 0.84 MEN1 (0.61) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL28972842 0.84 MEN1 (0.61) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL269482 0.84 NPC1 (1.00) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL600578 0.84 RAB9A (0.83) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL30114888 0.84 SMN1; SMN2 (0.61) MEN1KMT2ARAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
EP-1877481-B1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH PTE LTD (SG) 2016-02-17 EP disclosed
US-7842743-B2 Stabiliser composition for halide-containing polymers SUN ACE KAKOH (PTE.) LTD. (SG) 2010-11-30 US disclosed
US-20090030123-A1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2009-01-29 US disclosed
EP-1877481-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS Sun Ace Kakoh (Pte.) Ltd. (SG) 2008-01-16 EP disclosed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP disclosed
WO-2006110112-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2006-10-19 WO disclosed
WO-2006110106-A1 STABILISER COMPOSITION FOR CHLORINE-CONTAINING POLYMERS SUN ACE KAKOK (PTE.) LTD. (SG) 2006-10-19 WO disclosed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US disclosed
EP-0507013-B1 Process for the preparation of aromatic beta-diketones WITCO CORP (US) 1996-02-07 EP disclosed
EP-0507013-A1 Process for the preparation of aromatic beta-diketones WITCO CORPORATION (US) 1992-10-07 EP disclosed
US-5015777-A Reaction of an acetophenone and an aliphatic ester or an ester of benzoic acid in the presence of sodium alkoxide condensation agent in an aromatic solvent WITCO CORPORATION (US) 1991-05-14 US disclosed