SCHEMBL30001736

SCHEMBL30001736

Cc1cccc(C(=O)CC(=O)c2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.69
KMT2A Q03164 6/20 0.69
NPC1 O15118 3/20 0.69
RAB9A P51151 3/20 0.69
HPGD P15428 6/20 0.65
SMN1; SMN2 Q16637 5/20 0.65
MAPT P10636 5/20 0.65
KDM4E B2RXH2 4/20 0.65
CYP3A4 P08684 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
ALOX15 P16050 1/20 0.65
CES1 P23141 1/20 0.65
MAPK1 P28482 1/20 0.65
HTT P42858 3/20 0.59
NPSR1 Q6W5P4 3/20 0.59
LMNA P02545 2/20 0.59
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
POLB P06746 3/20 0.56
KCNK3 O14649 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675566 1.00 MEN1 (0.69) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL28728190 0.94 MEN1 (0.64) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL29456641 0.94 MEN1 (0.64) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL28972845 0.93 MEN1 (0.61) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL28972842 0.93 MEN1 (0.61) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL30114977 0.93 MEN1 (0.61) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL3674099 0.91 MEN1 (0.72) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL1421021 0.89 SMN1; SMN2 (0.58) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL875654 0.86 KMT2A (0.71) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL4834885 0.86 MEN1 (0.81) MEN1KMT2ANPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890881-B Method for simply synthesizing allyl dicarbonyl compound 南阳师范学院 2023-06-02 CN disclosed
CN-114890881-A Method for simply synthesizing allyl dicarbonyl compound 南阳师范学院 2022-08-12 CN disclosed