Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CBX7 | O95931 | 2/20 | 0.65 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.57 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449919 | 0.86 | ALDH1A1 (0.69) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL29458112 | 0.86 | ALDH1A1 (0.69) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL28459576 | 0.85 | ALDH1A1 (0.69) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL13274391 | 0.85 | ALDH1A1 (0.71) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL29458128 | 0.85 | ALDH1A1 (0.71) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL3487734 | 0.85 | ALDH1A1 (0.71) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL29458105 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL29458074 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL29458146 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 | |
| SCHEMBL28450277 | 0.83 | CBX7 (0.76) | ALDH1A1CBX7CDYLSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247982-B2 | NMDA receptor modulators, compositions comprising same and use of these compounds in the treatment of diseases involving the central nervous system | ADPUERIVITAM (FR) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247982-B2 | NMDA receptor modulators, compositions comprising same and use of these compounds in the treatment of diseases involving the central nervous system | GRIN3A, GRIN1, GRIN2A | ALDH1A1 4396/4885CBX7 4474/4885CDYL 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.