Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399032 | 1.00 | CHRNB2 (0.58) | CHRNB2CHRNA4HTR7CYP19A1GAA | |
| SCHEMBL21852317 | 0.86 | KCNH2 (0.51) | CHRNB2CHRNA4CYP19A1KDM4EKCNH2 | |
| SCHEMBL5509909 | 0.84 | CHRNB2 (0.59) | CHRNB2CHRNA4CYP19A1GAAKDM4E | |
| SCHEMBL4548252 | 0.84 | CHRNB2 (0.59) | CHRNB2CHRNA4CYP19A1GAAKDM4E | |
| SCHEMBL6750055 | 0.84 | CYP19A1 (0.59) | CYP19A1GAATSHRTDP1HTT | |
| SCHEMBL1219905 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4HTR7CYP19A1GAA | |
| SCHEMBL5275797 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4HTR7CYP19A1GAA | |
| SCHEMBL29458124 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4CYP19A1GAAKDM4E | |
| SCHEMBL7396303 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4CYP19A1GAAKDM4E | |
| SCHEMBL7445037 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4CYP19A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116635390-A | Potent and selective compounds as serotonin 1B receptor modulators | 莱科斯生物技术公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-4225753-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | Leukos Biotech, S.L. (ES) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022074103-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | LEUKOS BIOTECH, S.L. (ES) | 2022-04-14 | — | — | WO | disclosed |