Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383675 | 1.00 | L3MBTL1 (0.44) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL25384944 | 0.81 | L3MBTL1 (0.48) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL29458246 | 0.81 | L3MBTL1 (0.48) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL25383967 | 0.81 | L3MBTL1 (0.48) | L3MBTL1S1PR1CA12CA1CA2 | |
| SCHEMBL29458225 | 0.81 | L3MBTL1 (0.48) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL30616366 | 0.80 | LPL (0.43) | L3MBTL1LMNATSHRMAPTHPGD | |
| SCHEMBL26131069 | 0.80 | LPL (0.43) | L3MBTL1LMNATSHRMAPTHPGD | |
| SCHEMBL25384525 | 0.79 | HTT (0.46) | L3MBTL1S1PR1TSHRNFKB1RAB9A | |
| SCHEMBL29458129 | 0.79 | HTT (0.46) | L3MBTL1S1PR1TSHRNFKB1RAB9A | |
| SCHEMBL25383282 | 0.78 | L3MBTL1 (0.44) | L3MBTL1S1PR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225753-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | Leukos Biotech, S.L. (ES) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022074103-A1 | POTENT AND SELCTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS | LEUKOS BIOTECH, S.L. (ES) | 2022-04-14 | — | — | WO | disclosed |