SCHEMBL29458355

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	13/20	0.46

▸	BACE2	Q9Y5Z0	3/20	0.46

▸	CTSD	P07339	2/20	0.46

▸	FOLH1	Q04609	1/20	0.46

▸	ENPEP	Q07075	5/20	0.45

▸	NMT2	O60551	1/20	0.44

▸	NMT1	P30419	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29793051	0.95	BACE1 (0.49)	BACE1BACE2CTSDFOLH1ENPEP
SCHEMBL29630631	0.93	FOLH1 (0.54)	BACE1BACE2CTSDFOLH1NMT2
SCHEMBL30836809	0.93	FOLH1 (0.54)	BACE1BACE2CTSDFOLH1NMT2
SCHEMBL29391811	0.92	FOLH1 (0.48)	BACE1BACE2CTSDFOLH1ENPEP
SCHEMBL31406797	0.91	BACE1 (0.51)	BACE1BACE2CTSDFOLH1ENPEP
SCHEMBL29594791	0.90	BACE1 (0.52)	BACE1BACE2CTSD
SCHEMBL30288582	0.90	GRIN2D (0.49)	BACE1BACE2CTSDFOLH1ENPEP
SCHEMBL29364513	0.90	NMT2 (0.43)	FOLH1ENPEPNMT2NMT1
SCHEMBL11086609	0.90	FOLH1 (0.50)	BACE1BACE2CTSDFOLH1NMT2
SCHEMBL31400977	0.89	NMT1 (0.47)	BACE1BACE2CTSDNMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3966250-A2	PRECURSOR TRI-SPECIFIC ANTIBODY CONSTRUCTS AND METHODS OF USE THEREOF	Immunorizon Ltd. (IL)	2022-03-16	—	—	EP	disclosed