SCHEMBL29458677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29499556	0.87	MKNK2 (0.49)	MKNK2KDM4ESMN1; SMN2NPC1RAB9A
	SCHEMBL29473340	0.87	MKNK2 (0.49)	MKNK2KDM4ESMN1; SMN2NPC1RAB9A
	SCHEMBL15694859	0.83	KDM4E (0.52)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL15662417	0.81	KDM4E (0.50)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL3932209	0.80	NAPRT (0.53)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL30087468	0.78	DHODH (0.57)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL2301749	0.78	DHODH (0.57)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL9730378	0.78	MAPK8 (0.51)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL27931903	0.77	NAPRT (0.50)	NAPRTTDP1KDM4EDHODHL3MBTL1
	SCHEMBL2368857	0.75	MKNK2 (0.41)	MKNK2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.