SCHEMBL294590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12190885	0.95	CYP3A4 (0.47)	CYP3A4CYP2D6OPRK1POLBHSD17B10
	SCHEMBL12190875	0.91	CYP3A4 (0.43)	CYP3A4CYP2D6OPRK1POLBHSD17B10
	SCHEMBL9092070	0.84	CYP3A4 (0.43)	CYP3A4CYP2D6OPRK1POLBKMT2A
	SCHEMBL294230	0.84	LMNA (0.44)	CYP3A4CYP2D6OPRK1KMT2ALMNA
	SCHEMBL8623793	0.82	CYP3A4 (0.41)	CYP3A4CYP2D6OPRK1KMT2AMEN1
	SCHEMBL5050584	0.82	LMNA (0.49)	CYP3A4CYP2D6OPRK1KMT2AMEN1
	SCHEMBL12190871	0.80	CYP3A4 (0.47)	CYP3A4CYP2D6OPRK1POLBKMT2A
	SCHEMBL295286	0.79	KMT2A (0.44)	CYP3A4CYP2D6OPRK1POLBHSD17B10
	SCHEMBL9621330	0.78	KMT2A (0.45)	CYP3A4CYP2D6OPRK1KMT2ALMNA
	SCHEMBL295804	0.77	LMNA (0.45)	CYP3A4CYP2D6OPRK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.