Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.81 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376521 | 0.97 | SIGMAR1 (0.85) | SIGMAR1GNAI3GNAO1GNAI1CHRM5 | |
| SCHEMBL11697620 | 0.85 | SIGMAR1 (0.88) | SIGMAR1GNAI3GNAO1GNAI1CHRM5 | |
| SCHEMBL29001307 | 0.82 | SIGMAR1 (0.59) | SIGMAR1GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL15505725 | 0.81 | SIGMAR1 (0.57) | SIGMAR1BCHE | |
| SCHEMBL16269336 | 0.81 | SIGMAR1 (0.57) | SIGMAR1BCHE | |
| SCHEMBL2957913 | 0.81 | SIGMAR1 (0.57) | SIGMAR1BCHE | |
| Hydrochloric Acid SCHEMBL5547297 | 0.80 | SIGMAR1 (0.56) | SIGMAR1BCHE | |
| SCHEMBL23940316 | 0.79 | SIGMAR1 (0.56) | SIGMAR1GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL19032657 | 0.79 | SIGMAR1 (0.56) | SIGMAR1GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL23426277 | 0.79 | SIGMAR1 (0.56) | SIGMAR1GNAI3GNAO1GNAI1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749485-B2 | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH S.A. (CH) | 2010-07-06 | — | — | US | disclosed |
| US-20070196284-A1 | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH S.A. (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1153029-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000030688-A2 | AMPHIPATIC POLYCARBOXYLIC CHELATES AND COMPLEXES WITH PARAMAGNETIC METALS AS MRI CONTRAST AGENTS | BRACCO INTERNATIONAL B.V. (NL) | 2000-06-02 | — | — | WO | disclosed |