Asperulosidic Acid

Asperulosidic Acid

SCHEMBL29459346

CC(=O)OCC1=C[C@H](O)[C@@H]2C(C(=O)O)=CO[C@@H](O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ ELANE P08246 1/20 0.44
▸ STAT3 P40763 6/20 0.44
▸ PTPN1 P18031 5/20 0.44
▸ POLB P06746 1/20 0.43
▸ CTDSP1 Q9GZU7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asperulosidic Acid SCHEMBL422107 1.00 MAPT (0.52) MAPTL3MBTL1MEN1KMT2AELANE
SCHEMBL9057631 0.90 ELANE (0.55) MAPTL3MBTL1MEN1KMT2AELANE
SCHEMBL29425998 0.90 ELANE (0.46) MAPTL3MBTL1MEN1KMT2AELANE
Paederosidic Acid SCHEMBL424808 0.90 MAPT (0.50) MAPTL3MBTL1MEN1KMT2AELANE
Scandoside SCHEMBL29426072 0.88 L3MBTL1 (0.61) MAPTL3MBTL1MEN1KMT2AELANE
Scandoside SCHEMBL307654 0.88 L3MBTL1 (0.61) MAPTL3MBTL1MEN1KMT2AELANE
Scandoside SCHEMBL29682452 0.88 L3MBTL1 (0.61) MAPTL3MBTL1MEN1KMT2AELANE
SCHEMBL31228947 0.84 PTPN1 (0.57) MAPTPTPN1
SCHEMBL424407 0.83 MAPT (0.44) MAPTL3MBTL1MEN1KMT2AELANE
SCHEMBL29425962 0.83 L3MBTL1 (0.53) MAPTL3MBTL1MEN1KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11628195-B2 Method for preparing iridoid-rich noni fruit extract or fraction thereof, method for preparing immune-enhancing active material-rich noni fruit extract or fraction thereof and use of noni fruit extract or fraction thereof COSMAX NBT, INC. (KR) 2023-04-18 — — US claimed
US-20220080018-A1 METHOD FOR PREPARING IRIDOID-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF, METHOD FOR PREPARING IMMUNE-ENHANCING ACTIVE MATERIAL-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE OF NONI FRUIT EXTRACT OR FRACTION THEREOF COSMAX NBT, INC. (KR) 2022-03-17 — — US claimed
US-20240016876-A1 COMPOSITION FOR HANGOVER RELIEF COMPRISING NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE THEREOF COSMAX NBT, INC. (KR) 2024-01-18 — — US disclosed
CN-116528690-A Anti-hangover composition comprising noni extract or fractions thereof and use thereof 科丝美诗纽芝丽株式会社 2023-08-01 — — CN disclosed
US-11628195-B2 Method for preparing iridoid-rich noni fruit extract or fraction thereof, method for preparing immune-enhancing active material-rich noni fruit extract or fraction thereof and use of noni fruit extract or fraction thereof COSMAX NBT, INC. (KR) 2023-04-18 — — US disclosed
US-20220408777-A1 FOOD COMPOSITION FOR PREVENTING AND AMELIORATING DIABETES COMPRISING FERMENTED NONI AND METHOD FOR PREPARING SAME NSTBIO. CO., LTD. (KR) 2022-12-29 — — US disclosed
WO-2022145893-A1 COMPOSITION FOR RELIEVING STRESS COMPRISING FERMENTED AND AGED NONI AND CALAMANSI AS ACTIVE INGREDIENTS (주)엔에스티바이오 2022-07-07 — — WO disclosed
WO-2022145892-A1 COMPOSITION FOR ENHANCING EXERCISE PERFORMANCE AND FATIGUE RECOVERY, CONTAINING, AS ACTIVE INGREDIENT, FERMENTED AND AGED MORINDA CITRIFOLIA, COCONUT SUGAR OR MUSCOVADO SUGAR (주)엔에스티바이오 2022-07-07 — — WO disclosed
WO-2022108343-A1 COMPOSITION FOR HANGOVER RELIEF COMPRISING NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE THEREOF 코스맥스엔비티 주식회사 2022-05-27 — — WO disclosed
US-20220080018-A1 METHOD FOR PREPARING IRIDOID-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF, METHOD FOR PREPARING IMMUNE-ENHANCING ACTIVE MATERIAL-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE OF NONI FRUIT EXTRACT OR FRACTION THEREOF COSMAX NBT, INC. (KR) 2022-03-17 — — US disclosed
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