Paederosidic Acid

Paederosidic Acid

SCHEMBL424808

CSC(=O)OCC1=C[C@H](O)[C@@H]2C(C(=O)O)=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ PTPN1 P18031 6/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ ELANE P08246 1/20 0.43
▸ STAT3 P40763 6/20 0.42
▸ POLB P06746 1/20 0.41
▸ CTDSP1 Q9GZU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424407 0.93 MAPT (0.44) MAPTL3MBTL1PTPN1MEN1KMT2A
SCHEMBL423645 0.92 ELANE (0.46) MAPTL3MBTL1PTPN1MEN1KMT2A
SCHEMBL28912673 0.91 ELANE (0.53) MAPTMEN1KMT2AELANESTAT3
SCHEMBL29425847 0.91 ELANE (0.53) MAPTMEN1KMT2AELANESTAT3
SCHEMBL421492 0.91 ELANE (0.47) MAPTL3MBTL1PTPN1MEN1KMT2A
Asperulosidic Acid SCHEMBL29459346 0.90 MAPT (0.52) MAPTL3MBTL1PTPN1MEN1KMT2A
Asperulosidic Acid SCHEMBL422107 0.90 MAPT (0.52) MAPTL3MBTL1PTPN1MEN1KMT2A
Scandoside SCHEMBL307654 0.85 L3MBTL1 (0.61) MAPTL3MBTL1PTPN1MEN1KMT2A
Scandoside SCHEMBL29682452 0.85 L3MBTL1 (0.61) MAPTL3MBTL1PTPN1MEN1KMT2A
Scandoside SCHEMBL29426072 0.85 L3MBTL1 (0.61) MAPTL3MBTL1PTPN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112047983-B Paedenic acid monomer compound, preparation method and application thereof 宁波大昌药业有限公司 2023-02-03 — — CN claimed
CN-112730677-B UPLC-Q-TOF/MS method for detecting multiple chemical components in paederia scandens 成都中医药大学 2022-06-21 — — CN claimed
CN-112763600-B Method for simultaneously determining iridoid glycoside component content in fevervine based on HPLC 成都中医药大学 2022-03-29 — — CN claimed
CN-112851621-A Total iridoid extract of caulis et folium piperis, extraction and purification method and application thereof 汕头大学医学院 2021-05-28 — — CN claimed
CN-112763600-A Method for simultaneously determining iridoid glycoside component content in fevervine based on HPLC 成都中医药大学 2021-05-07 — — CN claimed
CN-112730677-A UPLC-Q-TOF/MS method for detecting multiple chemical components in paederia scandens 成都中医药大学 2021-04-30 — — CN claimed
CN-112047983-A Paedenitylic acid monomer compound, preparation method and application thereof 宁波大昌药业有限公司 2020-12-08 — — CN claimed
CN-112043755-A Paederia scandens extract, preparation method and application thereof 宁波大昌药业有限公司 2020-12-08 — — CN claimed
CN-112043756-A Dialysate of fevervine extract, preparation method and application thereof 宁波大昌药业有限公司 2020-12-08 — — CN claimed
CN-105348338-B The method of separation paederosidic acid is extracted from Hainan Island Saprosma ternatum 海南师范大学 2019-05-14 — — CN claimed
CN-106389455-B It is a kind of for preventing or treating the polymethoxyflavone, composition and its pharmaceutical preparation of nonalcoholic fatty liver 中国药科大学 2019-04-23 — — CN claimed
CN-106389455-A Polymethoxylated flavonoids for preventing or treating non-alcoholic fatty liver diseases, composition and medicine preparation thereof 中国药科大学 2017-02-15 — — CN claimed
CN-105348338-A Method for extracting and separating paederosidic acid from Saprosma merrillii Lo UNIV HAINAN NORMAL 2016-02-24 — — CN claimed
US-4410710-A Conversion of iridoids to prostaglandins RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 1983-10-18 — — US claimed
CN-120078865-A Medicinal tea composition, medicinal tea liquid and application thereof 新疆和田学院 2025-06-03 — — CN disclosed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 — — CN disclosed
CN-112851621-B Total iridoid extract of caulis et folium fici Tikouae, extraction and purification method and application thereof 汕头大学医学院 2023-03-17 — — CN disclosed
CN-1726975-A Chinese traditional medicine for treating coronar yheart disease an high blood pressure QIAO GUOQIANG (CN) 2006-02-01 — — CN disclosed
WO-1996010408-A1 CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) 1996-04-11 — — WO disclosed
US-4410710-A Conversion of iridoids to prostaglandins RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 1983-10-18 — — US disclosed
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