SCHEMBL29459459

SCHEMBL29459459

COc1cc([C@@H]2c3cc4c(cc3[C@H](O)[C@@H](CO)[C@@H]2C(=O)O)OCO4)cc(OC)c1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.61
POLB P06746 1/20 0.61
LMNA P02545 5/20 0.57
CYP3A4 P08684 5/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MAPT P10636 3/20 0.57
CYP2C9 P11712 2/20 0.57
MAPK1 P28482 2/20 0.57
CYP2C19 P33261 2/20 0.57
HIF1A Q16665 2/20 0.57
TUBB4A P04350 2/20 0.57
TUBB P07437 2/20 0.57
TUBA3C P0DPH7 2/20 0.57
TUBA1B P68363 2/20 0.57
TUBA4A P68366 2/20 0.57
TUBB4B P68371 2/20 0.57
TUBB3 Q13509 2/20 0.57
TUBB2A Q13885 2/20 0.57
TUBB8 Q3ZCM7 2/20 0.57
TUBA3E Q6PEY2 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016 1.00 NPSR1 (0.61) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL38655453 1.00 NPSR1 (0.61) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL28923858 0.93 NPSR1 (0.54) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL28165914 0.90 NPSR1 (0.51) NPSR1POLBLMNACYP3A4SMN1; SMN2
Podofilox SCHEMBL29363143 0.89 LMNA (0.77) NPSR1POLBLMNACYP3A4SMN1; SMN2
Podofilox SCHEMBL27708556 0.89 LMNA (0.77) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL20977542 0.88 NPSR1 (0.57) NPSR1POLBLMNACYP3A4SMN1; SMN2
Ethyl Picropodophyllate SCHEMBL27895488 0.88 NPSR1 (0.57) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL12964076 0.88 NPSR1 (0.57) NPSR1POLBLMNACYP3A4SMN1; SMN2
SCHEMBL9131949 0.88 NPSR1 (0.57) NPSR1POLBLMNACYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
CN-118451106-A Combination therapy of Claudin 18.2 antagonists and PD-1/PD-L1 axis inhibitors 苏州创胜医药集团有限公司 2024-08-06 CN claimed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 CN claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-117015387-A Attenuated cancer cells and methods relating thereto 加利福尼亚大学董事会 2023-11-07 CN claimed
CN-116829192-A Large pinocytosis selective monomer-drug conjugates 纽约大学 2023-09-29 CN claimed
CN-116806157-A Linker-payload and conjugates thereof 芬兰吉利科斯有限公司 2023-09-26 CN claimed
CN-116368384-A Compounds, targets and pathways for macrophage modulation 麻省理工学院 2023-06-30 CN claimed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN claimed
CN-116507617-B 1- (2- (4-Cyclopropyl-1H-1, 2, 3-triazol-1-yl) acetyl) -4-hydroxypyrrolidine-2-carboxamide derivatives as VHL inhibitors 基因泰克公司 2026-05-22 CN disclosed
CN-122029171-A Small molecule inhibitors of KRAS proteins 默沙东有限责任公司 2026-05-12 CN disclosed
CN-122028918-A TRIM7 inhibitors and uses thereof 沙塔克实验室有限公司 2026-05-12 CN disclosed
US-20260108512-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS HOTSPOT THERAPEUTICS INC (US) 2026-04-23 US disclosed
CN-120041380-A Without systemic immunosuppression allograft tolerance 西奈卫生系统公司 2025-05-27 CN disclosed
WO-2022169997-A1 LACTAMS AS CBL-B INHIBITORS GENENTECH, INC. (US) 2022-08-11 WO disclosed
WO-2022169998-A1 AMIDES AS CBL-B INHIBITORS GENENTECH, INC. (US) 2022-08-11 WO disclosed
WO-2022155587-A2 METHODS FOR DETECTING utDNA WASHINGTON UNIVERSITY (US) 2022-07-21 WO disclosed
EP-4025251-A1 METHODS OF TREATMENT USING A GENETICALLY MODIFIED AUTOLOGOUS T-CELL IMMUNOTHERAPY PACT Pharma, Inc. (US) 2022-07-13 EP disclosed
WO-2022076523-A1 METHODS AND COMPOSITIONS FOR IMAGING AND TREATING CANCER WASHINGTON UNIVERSITY (US) 2022-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108512-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS NR5A1, NR3C1, NR1H2 NPSR1 209/4885POLB 2686/4885LMNA 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.