Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | DNM2 | P50570 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23510582 | 0.76 | NR1I2 (0.37) | NR1I2CTSKKDM4EALDH1A1HPGD | |
| SCHEMBL14919680 | 0.74 | NR1I2 (0.35) | NR1I2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL17318941 | 0.74 | NR1I2 (0.35) | NR1I2KDM4EALDH1A1HPGDHTT | |
| SCHEMBL26489338 | 0.73 | TLR8 (0.34) | NR1I2 | |
| SCHEMBL23869472 | 0.73 | GPR84 (0.35) | NR1I2DNM2KDM4EHPGDGPR84 | |
| SCHEMBL29460862 | 0.73 | NR1I2 (0.37) | NR1I2MEN1KMT2A | |
| SCHEMBL21715700 | 0.72 | NR1I2 (0.33) | NR1I2GAA | |
| SCHEMBL29460859 | 0.72 | KDM4E (0.32) | NR1I2CTSLKDM4EALDH1A1HPGD | |
| SCHEMBL21431233 | 0.72 | KCNH2 (0.51) | CTSLCTSKTSHRHSD17B10CTSS | |
| SCHEMBL24971855 | 0.72 | TLR8 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149413-A | 3- ((hetero) aryl) -8-amino-2-oxo-1, 3-aza-spiro- [4.5] -decane derivatives | 格吕伦塔尔有限公司 | 2022-03-08 | — | — | CN | disclosed |