Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.33 |
| ▸ | ADA | P00813 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460897 | 0.73 | NR1I2 (0.36) | NR1I2MEN1KMT2A | |
| SCHEMBL24971855 | 0.73 | TLR8 (0.50) | ADA | |
| SCHEMBL18401337 | 0.72 | TLR8 (0.49) | ADA | |
| SCHEMBL26489338 | 0.71 | TLR8 (0.34) | NR1I2 | |
| SCHEMBL23869472 | 0.71 | GPR84 (0.35) | NR1I2FAAHADA | |
| SCHEMBL21715700 | 0.70 | NR1I2 (0.33) | NR1I2MAPT | |
| SCHEMBL22308557 | 0.70 | NR1I2 (0.40) | NR1I2LMNACYP3A4MAPTFAAH | |
| SCHEMBL26078439 | 0.70 | NR1I2 (0.40) | NR1I2LMNACYP3A4MAPTFAAH | |
| SCHEMBL4450757 | 0.70 | MEN1 (0.40) | NR1I2MEN1KMT2ALMNACHRM2 | |
| SCHEMBL29460891 | 0.70 | MEN1 (0.40) | NR1I2MEN1KMT2ALMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149413-A | 3- ((hetero) aryl) -8-amino-2-oxo-1, 3-aza-spiro- [4.5] -decane derivatives | 格吕伦塔尔有限公司 | 2022-03-08 | — | — | CN | disclosed |