Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.76 |
| ▸ | CKS1B | P61024 | 2/20 | 0.60 |
| ▸ | SKP1 | P63208 | 2/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461612 | 0.97 | GPR119 (0.72) | GPR119CKS1BSKP1SKP2CYP2D6 | |
| SCHEMBL4823523 | 0.97 | GPR119 (0.72) | GPR119CKS1BSKP1SKP2CYP2D6 | |
| SCHEMBL1459701 | 0.92 | GPR119 (0.79) | GPR119CKS1BSKP1SKP2CYP2D6 | |
| SCHEMBL30516861 | 0.92 | GPR119 (0.79) | GPR119CKS1BSKP1SKP2CYP2D6 | |
| SCHEMBL3487749 | 0.86 | GPR119 (1.00) | GPR119 | |
| SCHEMBL29461577 | 0.86 | HSD17B10 (0.76) | GPR119CYP2D6HSD17B10TSHRCYP2C19 | |
| SCHEMBL29461735 | 0.83 | HSD17B10 (0.76) | GPR119CYP2D6HSD17B10TSHRCYP2C19 | |
| SCHEMBL29461422 | 0.83 | GPR119 (0.66) | GPR119CYP2D6HSD17B10TSHRCYP2C19 | |
| SCHEMBL24290941 | 0.82 | GPR119 (0.65) | GPR119CKS1BSKP1SKP2POLB | |
| SCHEMBL22941868 | 0.82 | HSD17B10 (0.69) | GPR119CYP2D6HSD17B10TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230569-A | Thiohydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-03-25 | — | — | CN | disclosed |