Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | YAP1 | P46937 | 1/20 | 0.62 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.62 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 3/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Colfenamate SCHEMBL2110641 | 1.00 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL10597386 | 0.86 | LMNA (0.71) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL12715082 | 0.85 | LMNA (0.91) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL13299181 | 0.83 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL11494752 | 0.83 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL9271694 | 0.83 | RXFP1 (0.70) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL9270625 | 0.82 | RXFP1 (0.73) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| Ufenamate SCHEMBL36095 | 0.82 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL11520753 | 0.82 | LMNA (0.66) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| Ufenamate SCHEMBL29376700 | 0.82 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12226484-B2 | Compositions having improved bioavailability of therapeutics | TRx Biosciences Limited (GB) | 2025-02-18 | — | — | US | disclosed |
| CN-115066291-B | Aqueous capsule suspension concentrate based on polyurea shell material containing multifunctional aminocarboxylate | 拜耳公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118317956-A | Bis (hetero) aryl thioether oxadiazines as fungicidal compounds | 拜耳公司 | 2024-07-09 | — | — | CN | disclosed |
| US-20240075147-A1 | Compositions Having Improved Bioavailability of Therapeutics | TRx Biosciences Limited (GB) | 2024-03-07 | — | — | US | disclosed |
| EP-4312978-A2 | COMPOSITIONS HAVING IMPROVED BIOAVAILABILITY OF THERAPEUTICS | TRX Biosciences Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| CN-111741945-B | Crystalline forms | 先正达参股股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-110505874-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022207580-A2 | COMPOSITIONS HAVING IMPROVED BIOAVAILABILITY OF THERAPEUTICS | TRx Biosciences Limited (GB) | 2022-10-06 | — | — | WO | disclosed |
| CN-115135384-A | Benzimidazole compound or its salt, and agricultural and horticultural insecticide and acaricide containing the same and method of using the same | 日本农药株式会社 | 2022-09-30 | — | — | CN | disclosed |
| US-20220305125-A1 | Compositions Having Improved Bioavailability of Therapeutics | TRx Biosciences Limited (GB) | 2022-09-29 | — | — | US | disclosed |
| CN-110461839-B | JAK inhibitors containing 4-membered heterocyclic amides | 施万生物制药研发IP有限责任公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-110868861-B | Agricultural compositions | 萨卡帕·瓦达卡库塔 | 2022-03-15 | — | — | CN | disclosed |