Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794123 | 1.00 | NOD2 (0.57) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL7881984 | 0.84 | ALDH1A1 (0.50) | KMT2AKDM4EF10TSHRALDH1A1 | |
| SCHEMBL28264546 | 0.82 | MCL1 (0.44) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL7884814 | 0.82 | KDM4E (0.46) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL23045620 | 0.82 | ATM (0.44) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL31383475 | 0.82 | ATM (0.44) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL8689671 | 0.82 | NOD2 (0.47) | NOD2NOD1KDM4ETSHRATM | |
| SCHEMBL7806682 | 0.82 | KDM4E (0.55) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL3651263 | 0.81 | NOD2 (0.65) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL1092502 | 0.81 | KDM4E (0.62) | NOD2NOD1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302874-A | Indole carboxamide derivatives and pharmaceutical compositions comprising same | 国际药品株式会社 | 2022-04-08 | — | — | CN | disclosed |