Pyridazine

Pyridazine

SCHEMBL29463271

c1c[nH]cn1.c1c[nH]cn1.c1ccnnc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.72
FKBP5 Q13451 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridazine SCHEMBL527648 1.00 ALDH1A1 (0.72) ALDH1A1FKBP5
Pyridine SCHEMBL28331343 0.91 ALDH1A1 (0.59) ALDH1A1FKBP5
Imidazole SCHEMBL1767566 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL28641884 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Benzene SCHEMBL18279961 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Benzene SCHEMBL29168770 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Benzene SCHEMBL5088215 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL2635292 0.85
Imidazole SCHEMBL2684565 0.85 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331382 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111363119-B Preparation method of self-repairable polyurethane 湖南鑫振邦新材料有限公司 2023-03-28 CN disclosed
CN-111363119-B Preparation method of self-repairable polyurethane 湖南鑫振邦新材料有限公司 2023-03-28 CN disclosed
CN-112708102-B Synthesis of waterborne polyurethane dispersion containing quadruple hydrogen bonds based on ureido triazine structure and preparation method thereof 华南理工大学 2022-03-29 CN disclosed