Pyridazine

Pyridazine

SCHEMBL527648

c1c[nH]cn1.c1ccnnc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.72
FKBP5 Q13451 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridazine SCHEMBL29463271 1.00 ALDH1A1 (0.72) ALDH1A1FKBP5
Pyridine SCHEMBL28331343 0.91 ALDH1A1 (0.59) ALDH1A1FKBP5
Imidazole SCHEMBL1767566 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL28641884 0.86 ALDH1A1 (0.68) ALDH1A1FKBP5
Benzene SCHEMBL18279961 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Benzene SCHEMBL29168770 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Benzene SCHEMBL5088215 0.85 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL2635292 0.85
Imidazole SCHEMBL2684565 0.85 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331382 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021049597-A1 INSECTICIDE AGENT FOR AGRICULTURAL OR HORTICULTURAL USE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT EACH CONTAINING IMIDAZOPYRIDAZINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, AND USE OF SAID INSECTICIDE AGENT AND SAID CONTROL AGENT 日本農薬株式会社 2021-03-18 WO claimed
WO-2021049596-A1 AGRICULTURAL AND HORTICULTURAL INSECTICIDE OR ANIMAL ECTO- OR ENDO-PARASITE CONTROLLING AGENT WHICH CONTAINS IMIDAZOPYRIDAZINE COMPOUND HAVING SUBSTITUTED CYCLOPROPANE OXADIAZOLE GROUP OR SALTS THEREOF AS ACTIVE INGREDIENT, AND USAGE METHOD OF SAME 日本農薬株式会社 2021-03-18 WO claimed
CN-101824621-A High-performance copper and nickel protective agent HAINING COATECH METAL SURFACE TECHNOLOGY CO LTD 2010-09-08 CN claimed
EP-0568267-B1 Thermal transfer materials MINNESOTA MINING & MFG (US) 1997-01-22 EP claimed
US-5459260-A In vivo stability TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-10-17 US claimed
EP-0465078-B1 Infra-red sensitive photographic materials MINNESOTA MINING & MFG (US) 1995-06-28 EP claimed
EP-0568267-A2 Thermal transfer materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-03 EP claimed
US-5216166-A Cyanine dye with nitro group substituent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-01 US claimed
EP-0465078-A1 Infra-red sensitive photographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-08 EP claimed
WO-2024130341-A1 BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING Aculeus Therapeutics Pty Ltd (AU) 2024-06-27 WO disclosed
CN-116514708-A Pyridine-amide compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2023-08-01 CN disclosed
CN-116462635-A Pyrazine-1 (2H) -2-oxo compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2023-07-21 CN disclosed
CN-116425682-A Pyrimidine-1 (2H) -oxo compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2023-07-14 CN disclosed
US-20230062932-A1 COMPOUNDS CTXT PTY LTD. (AU) 2023-03-02 US disclosed
US-5216166-A Cyanine dye with nitro group substituent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-01 US disclosed
EP-0507313-A1 Polycyclic carbapenem compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-07 EP disclosed
EP-0267483-B1 PROCESS AND ELEMENT FOR OBTAINING A PHOTOGRAPHIC IMAGE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-22 EP disclosed
EP-0465078-A1 Infra-red sensitive photographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-08 EP disclosed
US-4812390-A MIXTURE OF OPTICAL AND CHEMICAL SENSITIZED SILVER HALIDE GRAINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-14 US disclosed
EP-0267483-A2 Process and element for obtaining a photographic image MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230062932-A1 COMPOUNDS STING1, IRF3, MAVS ALDH1A1 4079/4885FKBP5 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.