Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | FEN1 | P39748 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925036 | 1.00 | ALOX5AP (0.34) | ALOX5APFEN1L3MBTL1PKMHSD11B1 | |
| SCHEMBL29464324 | 0.82 | HSD11B1 (0.38) | L3MBTL1PKMHSD11B1CTSDBACE1 | |
| SCHEMBL19968754 | 0.82 | HSD11B1 (0.38) | L3MBTL1PKMHSD11B1CTSDBACE1 | |
| SCHEMBL29464534 | 0.82 | PIK3CD (0.40) | L3MBTL1HSD11B1ALDH1A1KDM4EHPGD | |
| SCHEMBL19925031 | 0.82 | PIK3CD (0.40) | L3MBTL1HSD11B1ALDH1A1KDM4EHPGD | |
| SCHEMBL29464408 | 0.79 | L3MBTL1 (0.36) | ALOX5APFEN1L3MBTL1HSD11B1TSHR | |
| SCHEMBL19925044 | 0.79 | L3MBTL1 (0.36) | ALOX5APFEN1L3MBTL1HSD11B1TSHR | |
| SCHEMBL22323144 | 0.77 | SCN1A (0.40) | L3MBTL1PKMHSD11B1ALDH1A1SCN1A | |
| SCHEMBL29464473 | 0.77 | SCN9A (0.44) | HSD11B1ALDH1A1KDM4E | |
| SCHEMBL19925056 | 0.77 | SCN9A (0.44) | HSD11B1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |