Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925111 | 1.00 | SLC40A1 (0.41) | SLC40A1MAPTPKMMEN1KMT2A | |
| SCHEMBL19925178 | 0.89 | MAPT (0.46) | SLC40A1MAPTPKMMEN1KMT2A | |
| SCHEMBL29464394 | 0.89 | MAPT (0.46) | SLC40A1MAPTPKMMEN1KMT2A | |
| SCHEMBL29464473 | 0.80 | SCN9A (0.44) | MEN1KMT2AALDH1A1HSD11B1KDM4E | |
| SCHEMBL19925056 | 0.80 | SCN9A (0.44) | MEN1KMT2AALDH1A1HSD11B1KDM4E | |
| SCHEMBL19968754 | 0.79 | HSD11B1 (0.38) | SLC40A1PKMALDH1A1RXFP1HSD11B1 | |
| SCHEMBL29464324 | 0.79 | HSD11B1 (0.38) | SLC40A1PKMALDH1A1RXFP1HSD11B1 | |
| SCHEMBL19925031 | 0.78 | PIK3CD (0.40) | MEN1KMT2AALDH1A1HSD11B1L3MBTL1 | |
| SCHEMBL29464534 | 0.78 | PIK3CD (0.40) | MEN1KMT2AALDH1A1HSD11B1L3MBTL1 | |
| SCHEMBL15556437 | 0.78 | MAPT (0.49) | SLC40A1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |