Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 12/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951309 | 1.00 | RBP4 (0.34) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL29464399 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL19933338 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL19951386 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL19927756 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL29464499 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL29464304 | 0.95 | SCN9A (0.33) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL19925001 | 0.95 | RORC (0.35) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL29464323 | 0.95 | RORC (0.35) | RBP4TTRSCN9AKIF18ARORC | |
| SCHEMBL22323445 | 0.89 | RBP4 (0.33) | RBP4TTRSCN9AKIF18APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |