Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927805 | 1.00 | HSD11B1 (0.40) | HSD11B1ADORA2ASLC22A12SCN9AL3MBTL1 | |
| SCHEMBL29464317 | 0.91 | HSD11B1 (0.42) | HSD11B1SLC22A12SCN9AHSP90AA1HSP90AB1 | |
| SCHEMBL19925025 | 0.91 | HSD11B1 (0.42) | HSD11B1SLC22A12SCN9AHSP90AA1HSP90AB1 | |
| SCHEMBL29464516 | 0.84 | HSD11B1 (0.38) | HSD11B1SCN9AL3MBTL1 | |
| SCHEMBL19928762 | 0.84 | HSD11B1 (0.38) | HSD11B1SCN9AL3MBTL1 | |
| SCHEMBL19925022 | 0.84 | SCN9A (0.42) | SLC22A12SCN9A | |
| SCHEMBL29464358 | 0.84 | SCN9A (0.42) | SLC22A12SCN9A | |
| SCHEMBL29464324 | 0.83 | HSD11B1 (0.38) | HSD11B1ADORA2ASCN9AL3MBTL1 | |
| SCHEMBL19968754 | 0.83 | HSD11B1 (0.38) | HSD11B1ADORA2ASCN9AL3MBTL1 | |
| SCHEMBL19925179 | 0.82 | HSD11B1 (0.46) | HSD11B1SLC22A12SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |