Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925123 | 1.00 | PSMB1 (0.37) | PSMB1PSMB5PSMB2PIK3CDPIK3CG | |
| SCHEMBL19925031 | 0.86 | PIK3CD (0.40) | PSMB1PSMB5PSMB2PIK3CDPIK3CG | |
| SCHEMBL29464534 | 0.86 | PIK3CD (0.40) | PSMB1PSMB5PSMB2PIK3CDPIK3CG | |
| SCHEMBL29464309 | 0.82 | SCN1A (0.37) | PSMB1PSMB5PSMB2CA12CA1 | |
| SCHEMBL19925171 | 0.82 | SCN1A (0.37) | PSMB1PSMB5PSMB2CA12CA1 | |
| SCHEMBL29464316 | 0.81 | PIK3CG (0.36) | PSMB1PSMB5PSMB2PIK3CDPIK3CG | |
| SCHEMBL19925745 | 0.81 | PIK3CG (0.36) | PSMB1PSMB5PSMB2PIK3CDPIK3CG | |
| SCHEMBL29464507 | 0.80 | L3MBTL1 (0.43) | PIK3CDPIK3CGPOLBLMNACYP2C9 | |
| SCHEMBL19927806 | 0.80 | L3MBTL1 (0.43) | PIK3CDPIK3CGPOLBLMNACYP2C9 | |
| SCHEMBL23770767 | 0.77 | ALOX5AP (0.34) | KDM4EHSD17B10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |