Neuropeptide S

Neuropeptide S

SCHEMBL29464558

CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.61
▸ GLP1R P43220 2/20 0.58
▸ GCGR P47871 1/20 0.58
▸ GIPR P48546 1/20 0.58
▸ PTH1R Q03431 3/20 0.58
▸ VIPR1 P32241 1/20 0.57
▸ OPRL1 P41146 5/20 0.56
▸ CCKBR P32239 1/20 0.56
▸ RXFP1 Q9HBX9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31719706 0.95 TFPI (0.65) TFPIVIPR1OPRL1
SCHEMBL30431350 0.92 OPRL1 (0.59) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL29640388 0.91 TFPI (0.65) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL31182903 0.90 TFPI (0.65) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL30358174 0.89 PTH1R (0.62) GLP1RPTH1RVIPR1OPRL1CCKBR
SCHEMBL29701273 0.88 TFPI (0.74) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL30176428 0.88 PTH1R (0.70) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL30436591 0.88 VIPR1 (0.65) TFPIGLP1RGCGRGIPRPTH1R
SCHEMBL29964966 0.88 PTH1R (0.62) GLP1RPTH1RVIPR1CCKBRRXFP1
SCHEMBL30139095 0.88 PTH1R (0.59) GLP1RPTH1RVIPR1CCKBRRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250354213-A1 METHODS RELATING TO RESPIRATORY HEALTH THERAPEUTICS UNIV NORTHWESTERN (US) 2025-11-20 — — US claimed
US-20250320559-A1 METHODS RELATING TO IMPAIRED RESPIRATORY HEALTH THERAPEUTICS UNIV NORTHWESTERN (US) 2025-10-16 — — US claimed
US-12297227-B2 Method for extracting target protein from biological sample and method for analyzing target protein MEDIFORD CORPORATION (JP) 2025-05-13 — — US claimed
EP-4525969-A1 DEVICES FOR TREATING STRESS AND IMPROVING ALERTNESS USING ELECTRICAL STIMULATION Spark Biomedical, Inc. (US) 2025-03-26 — — EP claimed
CN-119604527-A Anti-programmed death ligand 1 (PD-L1) antibodies 安得泰医药有限公司 2025-03-11 — — CN claimed
CN-119367513-A Application of neuropeptide S in promoting EMSCs to treat spinal cord injury 江南大学 2025-01-28 — — CN claimed
CN-119213061-A Cross-linked protein, method for producing the same and use thereof 纽约州立大学研究基金会 2024-12-27 — — CN claimed
EP-3440051-B1 NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS RES TRIANGLE INST (US) 2024-03-20 — — EP claimed
WO-2023224636-A1 DEVICES FOR TREATING STRESS AND IMPROVING ALERTNESS USING ELECTRICAL STIMULATION Spark Biomedical, Inc. (US) 2023-11-23 — — WO claimed
CN-117098768-A Biologically reactive compounds and methods of use thereof 加利福尼亚大学董事会 2023-11-21 — — CN claimed
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 — — EP claimed
CN-114712484-B Application of neuropeptide S in preparation of medicine for preventing and treating motion sickness 中山大学 2023-07-04 — — CN claimed
EP-2981292-B1 SUPRAMOLECULAR AGGREGATES COMPRISING A MALEIMIDO CORE UFPEPTIDES S R L (IT) 2022-11-02 — — EP claimed
US-20220237496-A1 QUANTUM MEMORY AND ASSOCIATED APPLICATIONS CADET, Xavier (FR) 2022-07-28 — — US claimed
CN-114712484-A Application of neuropeptide S in preparation of medicine for preventing and treating motion sickness 中山大学 2022-07-08 — — CN claimed
US-20220133839-A1 PEPTIDE ANALOGUES WITH BRANCHED AMINO ACID PROBE(S) TXP PHARMA GMBH (CH) 2022-05-05 — — US claimed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 — — WO claimed
CN-109153635-B Neuropeptide S receptor (NPSR) agonists 研究三角协会 2022-04-08 — — CN claimed
EP-4739335-A1 INTRANASAL DELIVERY Virpax Pharmaceuticals Inc. (US) 2026-05-13 — — EP disclosed
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF TRANSLATE BIO, INC. 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF NSUN3, TRDMT1, NSUN2 TFPI 4804/4885GLP1R 3267/4885GCGR 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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