Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 10/20 | 0.41 |
| ▸ | FEN1 | P39748 | 10/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946461 | 1.00 | ALOX5AP (0.41) | ALOX5APFEN1TRPA1GPR3PDE3B | |
| SCHEMBL2946467 | 1.00 | ALOX5AP (0.41) | ALOX5APFEN1TRPA1GPR3PDE3B | |
| SCHEMBL2946464 | 1.00 | ALOX5AP (0.41) | ALOX5APFEN1TRPA1GPR3PDE3B | |
| SCHEMBL4932481 | 0.77 | GPR3 (0.38) | GPR3 | |
| SCHEMBL4932491 | 0.77 | GPR3 (0.38) | GPR3 | |
| SCHEMBL2950123 | 0.76 | ALOX5AP (0.50) | ALOX5APFEN1TRPA1PDE3BPDE3A | |
| SCHEMBL14809450 | 0.74 | GRIN2D (0.45) | GPR3 | |
| SCHEMBL1890675 | 0.74 | GRIN2D (0.45) | GPR3 | |
| SCHEMBL1890678 | 0.74 | GRIN2D (0.45) | GPR3 | |
| SCHEMBL14809451 | 0.74 | GRIN2D (0.45) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |