Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19406510 | 1.00 | CA12 (0.41) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL29412538 | 0.71 | KDM4E (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8011773 | 0.69 | KEAP1 (0.42) | KEAP1GPR3MAOA | |
| SCHEMBL19695681 | 0.65 | KEAP1 (0.36) | KEAP1GPR3MAOA | |
| SCHEMBL14907206 | 0.64 | CA12 (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8517114 | 0.62 | CA12 (0.41) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4423134 | 0.62 | KEAP1 (0.38) | KEAP1GPR3MAOA | |
| SCHEMBL88858 | 0.62 | CA12 (0.45) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL29398807 | 0.62 | CA12 (0.45) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL12341038 | 0.62 | NPC1 (0.42) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114059090-B | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2023-11-21 | — | — | CN | claimed |
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114059090-B | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114059090-B | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114059090-B | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | disclosed |