Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398807 | 1.00 | CA12 (0.45) | CA12CA1CA2CA9GPR3 | |
| SCHEMBL28201382 | 0.98 | CA12 (0.44) | CA12CA1CA2CA9GPR3 | |
| Hydrochloric Acid SCHEMBL9756819 | 0.98 | CA12 (0.44) | CA12CA1CA2CA9GPR3 | |
| Isobutane SCHEMBL9756824 | 0.92 | CA12 (0.40) | CA12CA1CA2CA9GPR3 | |
| Acetic Acid SCHEMBL6200962 | 0.88 | CA12 (0.38) | CA12CA1CA2CA9KMT2A | |
| Hydrochlorthiazide SCHEMBL6036314 | 0.81 | CA12 (0.33) | CA12CA1CA2CA9 | |
| Oxazole SCHEMBL4863479 | 0.81 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL29429784 | 0.80 | CA12 (0.42) | CA12CA1CA2CA9GPR3 | |
| SCHEMBL11256812 | 0.77 | CA12 (0.35) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL5613160 | 0.74 | CA12 (0.40) | CA12CA1CA2CA9GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250160275-A1 | COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-05-22 | — | — | US | claimed |
| EP-4380937-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS | Rayzebio, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| CN-118176194-A | Conjugates comprising covalent binding agents for targeting intracellular proteins | 瑞择生物公司 | 2024-06-11 | — | — | CN | claimed |
| WO-2024085725-A1 | NOVEL COMPOUND DERIVATIVE AND PHARMACOLOGICAL USE THEREOF | 고려대학교 산학협력단 | 2024-04-25 | — | — | WO | claimed |
| CN-116676605-A | Synthesis method of benzo [ d ] imidazo [1,5-b ] isothiazole-5, 5-dioxide derivative | 湖南科技学院 | 2023-09-01 | — | — | CN | claimed |
| WO-2023164606-A1 | COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-31 | — | — | WO | claimed |
| WO-2023014988-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS | RAYZEBIO, INC. (US) | 2023-02-09 | — | — | WO | claimed |
| CN-103254151-A | Benzisoxa thiazoles 5-LOX and mPGES-1 inhibitor and application | UNIV BEIJING | 2013-08-21 | — | — | CN | claimed |
| US-20060199838-A1 | Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies | PROTAMED, INC. | 2006-09-07 | — | — | US | claimed |
| CN-1817134-A | Antimicrobial composition for agriculture and horticulture | SUMITOMO CHEMICAL CO (JP) | 2006-08-16 | — | — | CN | claimed |
| US-5374738-A | Reacting a saccharin salt with magnessium grignard reagent in low level of anhydrous solvent to form chemical intermediates, hydrolysis with water | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-12-20 | — | — | US | claimed |
| EP-0446982-B1 | Low-temperature bleaching compositions | UNILEVER NV (NL) | 1994-10-26 | — | — | EP | claimed |
| EP-0453003-B1 | Bleach catalysts and compositions containing same | UNILEVER NV (NL) | 1994-10-05 | — | — | EP | claimed |
| EP-0453003-A2 | Bleach catalysts and compositions containing same | UNILEVER N.V. (NL) | 1991-10-23 | — | — | EP | claimed |
| EP-0446982-A2 | Low-temperature bleaching compositions | UNILEVER N.V. (NL) | 1991-09-18 | — | — | EP | claimed |
| US-5047163-A | Low Temperature Bleaching Composition Containing A Peroxygen Compound, A Sulfonimine Oxygen Transfer Agent Activator And A! Bleach Percursor | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-09-10 | — | — | US | claimed |
| US-5041232-A | Inlcudes peroxygen compound and surfactant | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-08-20 | — | — | US | claimed |
| EP-0162494-A1 | Process for the preparation of a 3-hydroxy-2,3-dihydrobenzisothiazole 1,1-dioxide and the use of this compound as a biocide and for preparing an ortho-sulphobenzimide | AKZO N.V. (NL) | 1985-11-27 | — | — | EP | claimed |
| US-4283537-A | Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation | POLAROID CORPORATION (US) | 1981-08-11 | — | — | US | claimed |
| US-4178447-A | Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides | POLAROID CORPORATION (US) | 1979-12-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199838-A1 | Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies | IAPP, SNCA, BACE2 | CA12 3829/4885CA1 4580/4885CA2 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.