Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376744 | 1.00 | ALDH1A1 (0.33) | ALDH1A1KCNJ1 | |
| SCHEMBL14775276 | 0.82 | — | — | |
| SCHEMBL26920416 | 0.80 | SGK1 (0.33) | ALDH1A1 | |
| SCHEMBL29844672 | 0.78 | KCNJ1 (0.46) | ALDH1A1KCNJ1 | |
| SCHEMBL22678487 | 0.78 | KCNJ1 (0.46) | ALDH1A1KCNJ1 | |
| SCHEMBL29956623 | 0.78 | CDK2 (0.35) | ALDH1A1 | |
| SCHEMBL30901440 | 0.77 | PDCD1 (0.45) | — | |
| SCHEMBL21290658 | 0.77 | PDCD1 (0.45) | — | |
| SCHEMBL23214420 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KCNJ1 | |
| SCHEMBL29955836 | 0.74 | GRM5 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772157-A | Synthesis method of 6-chloro-1H-pyrazolo [3,4-B ] pyrazine | 浙江江北南海药业有限公司 | 2024-10-15 | — | — | CN | claimed |
| WO-2025092905-A1 | PARP INHIBITORS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025091346-A1 | PARP INHIBITORS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| CN-118772157-A | Synthesis method of 6-chloro-1H-pyrazolo [3,4-B ] pyrazine | 浙江江北南海药业有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118772157-A | Synthesis method of 6-chloro-1H-pyrazolo [3,4-B ] pyrazine | 浙江江北南海药业有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118084940-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117263942-A | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116731038-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-112166110-B | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-3515916-B1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11529347-B2 | SHP2 phosphatase inhibitors and methods of use thereof | RELAY THERAPEUTICS, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| EP-3983413-A1 | SUBSTITUTED PYRAZOLO-PYRAZINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529347-B2 | SHP2 phosphatase inhibitors and methods of use thereof | PTPN21, PTPN22, PTPN5 | ALDH1A1 4124/4885KCNJ1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.