Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 14/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956623 | 0.83 | CDK2 (0.35) | GRM5CDK2MAPKAPK2ALDH1A1SIRT6 | |
| SCHEMBL28762410 | 0.78 | PLAU (0.35) | — | |
| SCHEMBL29952131 | 0.77 | ATR (0.37) | GRM5 | |
| SCHEMBL13606495 | 0.77 | ATR (0.37) | GRM5 | |
| SCHEMBL23214420 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL17418797 | 0.75 | MAPKAPK2 (0.39) | GRM5CDK2MAPKAPK2ALDH1A1 | |
| SCHEMBL29465769 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL376744 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1560727 | 0.72 | — | — | |
| SCHEMBL30743728 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |