Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240162 | 0.94 | HTR1A (0.57) | TYRTTRNFE2L2HTR1AAPP | |
| SCHEMBL391171 | 0.94 | TYR (0.67) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL20875273 | 0.94 | TYR (0.67) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL29450556 | 0.94 | TYR (0.67) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL31336321 | 0.88 | TYR (0.56) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL23037096 | 0.87 | TRPA1 (0.59) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL29869374 | 0.87 | TRPA1 (0.59) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL10425913 | 0.87 | TRPA1 (0.59) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL10423557 | 0.84 | TYR (0.55) | TYRTTRNFE2L2APPCYP2D6 | |
| SCHEMBL8756909 | 0.84 | TYR (0.55) | TYRTTRNFE2L2APPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113413439-B | Traditional Chinese medicine formula for treating Alzheimer's disease and preparation method of compound preparation of traditional Chinese medicine formula | 中山创天生物科技有限公司 | 2022-03-29 | — | — | CN | disclosed |