SCHEMBL29467708

SCHEMBL29467708

CC(C)(CCC(=O)O)SSc1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
EHMT2 Q96KQ7 1/20 0.44
EHMT1 Q9H9B1 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
HPGD P15428 3/20 0.39
RAB9A P51151 3/20 0.39
HSD17B10 Q99714 2/20 0.39
NPC1 O15118 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
BLM P54132 1/20 0.38
CYP2D6 P10635 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10086906 1.00 ALDH1A1 (0.54) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL9197696 0.85 ALDH1A1 (0.49) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL17047628 0.85 ALDH1A1 (0.45) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL20740183 0.81 LMNA (0.40) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL18856002 0.80 EHMT2 (0.52) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL19578400 0.80 KMT2A (0.41) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL20993559 0.80 KMT2A (0.41) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL19578402 0.80 KMT2A (0.41) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL9885501 0.79 ALDH1A1 (0.39) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL28578500 0.79 LMNA (0.45) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082772-A1 ANTIBODY-DRUG CONJUGATE Genahead Bio, Inc. (JP) 2025-03-13 US disclosed
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN disclosed
CN-113039191-B Nucleotide analogues 奇异基因组学系统公司 2024-07-16 CN disclosed
EP-4212176-A1 ANTIBODY-DRUG CONJUGATE Genahead Bio, Inc. (JP) 2023-07-19 EP disclosed
CN-109912683-B Cytotoxin molecule, conjugate, preparation method and application thereof 杭州多禧生物科技有限公司 2023-01-06 CN disclosed
EP-3210627-B1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO LTD (CN) 2022-12-21 EP disclosed
WO-2022078524-A4 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-08 WO disclosed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN disclosed
EP-3473270-B1 ANTIBODY-DRUG CONJUGATE GENAHEAD BIO INC (JP) 2022-11-30 EP disclosed
WO-2022154127-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED THEREFROM 味の素株式会社 2022-07-21 WO disclosed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250082772-A1 ANTIBODY-DRUG CONJUGATE CD63, CD99, CD74 ALDH1A1 319/4885EHMT2 3044/4885EHMT1 3090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.