Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.41 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329827 | 1.00 | FGFR1 (0.49) | FGFR1FLT1ITKELANELRRK2 | |
| SCHEMBL24330017 | 0.94 | FGFR1 (0.46) | FGFR1FLT1ITKELANELRRK2 | |
| SCHEMBL30611154 | 0.94 | FGFR1 (0.46) | FGFR1FLT1ITKELANELRRK2 | |
| SCHEMBL30611155 | 0.89 | MGLL (0.43) | FGFR1FLT1ITKFAAHABL1 | |
| SCHEMBL24330415 | 0.89 | MGLL (0.43) | FGFR1FLT1ITKFAAHABL1 | |
| SCHEMBL30611147 | 0.89 | FAAH (0.42) | FGFR1FLT1ITKLRRK2PRKDC | |
| SCHEMBL24331242 | 0.89 | FAAH (0.42) | FGFR1FLT1ITKPRKDCFAAH | |
| SCHEMBL24331238 | 0.89 | FAAH (0.42) | FGFR1FLT1ITKLRRK2PRKDC | |
| SCHEMBL30611117 | 0.89 | FAAH (0.42) | FGFR1FLT1ITKPRKDCFAAH | |
| SCHEMBL24330165 | 0.88 | FGFR1 (0.43) | FGFR1FLT1PRKDCFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568684-A | Novel compounds | AC免疫有限公司 | 2023-08-08 | — | — | CN | claimed |
| EP-4229052-A1 | NOVEL COMPOUNDS | AC Immune SA (CH) | 2023-08-23 | — | — | EP | disclosed |
| CN-116568684-A | Novel compounds | AC免疫有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |