SCHEMBL29468652

SCHEMBL29468652

Cc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 20/20 1.00
ADRA1B P35368 19/20 1.00
ADRA1D P25100 16/20 1.00
CYP3A4 P08684 1/20 0.83
CYP2C9 P11712 1/20 0.83
CYP2C19 P33261 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7822496 1.00 ADRA1A (1.00) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Fumaric Acid SCHEMBL7830732 0.93 ADRA1A (0.87) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Fumaric Acid SCHEMBL7830468 0.93 ADRA1A (0.87) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
SCHEMBL7832378 0.91 ADRA1A (1.00) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Bromide SCHEMBL7834162 0.91 ADRA1A (0.83) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Hydrochloric Acid SCHEMBL7832255 0.91 ADRA1A (0.98) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
SCHEMBL6802383 0.91 ADRA1A (1.00) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Hydrochloric Acid SCHEMBL7833241 0.90 ADRA1A (0.98) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
Hydrochloric Acid SCHEMBL7833110 0.90 ADRA1A (0.98) ADRA1AADRA1BADRA1DCYP3A4CYP2C9
SCHEMBL9044556 0.90 ADRA1A (0.83) ADRA1AADRA1BADRA1DCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
WO-2023172240-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO claimed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US disclosed
US-20250041211-A1 OPHTHALMIC PREPARATION AND APPLICATION THEREOF IN TREATMENT OF PRESBYOPIA Eye Hospital, Wenzhou Medical University (CN) 2025-02-06 US disclosed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP disclosed
EP-4489746-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP disclosed
US-20240423970-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-12-26 US disclosed
US-12102628-B2 Composition and methods for the treatment of myopia Seinda Pharmaceutical Guangzhou Corporation 2024-10-01 US disclosed
EP-3654964-B1 COMPOSITION COMPRISING ATROPINE AND A MIOTIC AGENT AND ITS USE IN THE TREATMENT OF MYOPIA SEINDA PHARMACEUTICAL GUANGZHOU CORP (CN) 2024-04-24 EP disclosed
WO-2023172840-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO disclosed
WO-2023172240-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO disclosed
US-20230277521-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC 2023-09-07 US disclosed
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA Seinda Pharmaceutical Guangzhou Corporation (CN) 2023-03-02 US disclosed
US-11285141-B2 Composition and methods for the treatment of myopia Seinda Pharmaceutical Guangzhou Corporation (CN) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12102628-B2 Composition and methods for the treatment of myopia CHRM3, CHRM2, MYOC ADRA1A 74/4885ADRA1B 63/4885ADRA1D 99/4885
US-11285141-B2 Composition and methods for the treatment of myopia CHRM3, CHRM2, MYOC ADRA1A 74/4885ADRA1B 63/4885ADRA1D 99/4885
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA CHRM3, CHRM2, MYOC ADRA1A 74/4885ADRA1B 63/4885ADRA1D 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.