Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28315214 | 1.00 | DYRK1A (0.38) | DYRK1ATSHRHPGDKDM4EHSD17B10 | |
| SCHEMBL25990458 | 0.79 | DYRK1A (0.41) | DYRK1ATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL28327209 | 0.79 | CTSS (0.34) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL27957289 | 0.79 | TSHR (0.42) | TSHRHPGDKDM4EHSD17B10PGK1 | |
| Hydrochloric Acid SCHEMBL27701462 | 0.77 | TSHR (0.47) | TSHRHPGDKDM4EHSD17B10PGK1 | |
| SCHEMBL2693979 | 0.77 | PGK1 (0.34) | TSHRPGK1ADORA2AADORA1CYP3A4 | |
| SCHEMBL2694746 | 0.76 | PGK1 (0.33) | PGK1 | |
| SCHEMBL27346612 | 0.76 | KCNH2 (0.34) | TSHRHPGDKDM4EHSD17B10PGK1 | |
| SCHEMBL976427 | 0.76 | PIP4K2A (0.39) | DYRK1ATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL30674328 | 0.75 | DYRK1A (0.38) | DYRK1ATSHRKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228761-A1 | 2-OXO-DIHYDROQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS GABA TYPE A RECEPTOR MODULATORS | University College Cardiff Consultants Limited (GB) | 2023-08-23 | — | — | EP | disclosed |
| CN-116472042-A | 2-oxo-dihydroquinoline-3-carboxamide derivatives as modulators of GABA A type receptors | 加的夫大学学院咨询有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2022079432-A1 | 2-OXO-DIHYDROQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS GABA TYPE A RECEPTOR MODULATORS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-04-21 | — | — | WO | disclosed |