SCHEMBL29468902

SCHEMBL29468902

C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](COC(C)(C)C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.47
▸ XIAP P98170 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ CAPN1 P07384 4/20 0.42
▸ CMA1 P23946 7/20 0.42
▸ CTSB P07858 1/20 0.42
▸ SLC6A2 P23975 1/20 0.39
▸ ITGB1 P05556 1/20 0.39
▸ ITGA4 P13612 1/20 0.39
▸ ELANE P08246 1/20 0.39
▸ OPRM1 P35372 1/20 0.38
▸ OPRD1 P41143 1/20 0.38
▸ OPRK1 P41145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30852860 0.92 CAPN1 (0.48) GRB2XIAPCAPN1CTSBOPRM1
SCHEMBL30543482 0.88 GRB2 (0.52) GRB2OPRM1
SCHEMBL30543490 0.88 CMA1 (0.42) GRB2XIAPKMT2ACAPN1CMA1
SCHEMBL29396765 0.85 CAPN1 (0.52) GRB2XIAPCAPN1CTSBSLC6A2
SCHEMBL30455247 0.85 CAPN1 (0.52) GRB2XIAPCAPN1CTSBSLC6A2
SCHEMBL29468766 0.84 GRB2 (0.42) GRB2XIAPKMT2ACAPN1CMA1
SCHEMBL29468837 0.83 KMT2A (0.41) GRB2KMT2ACMA1ITGB1ITGA4
SCHEMBL29641846 0.82 GRB2 (0.51) GRB2XIAPCAPN1CMA1CTSB
SCHEMBL30028577 0.82 KMT2A (0.45) XIAPKMT2ACMA1ITGB1ITGA4
SCHEMBL30972553 0.80 KMT2A (0.42) KMT2ACMA1ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622948-B2 GLP-1/GIP dual agonists SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2026-05-12 — — US disclosed
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2024-12-26 — — US disclosed
EP-4436991-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Sun Pharmaceutical Industries Limited (IN) 2024-10-02 — — EP disclosed
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL IND LTD (IN) 2023-08-03 — — US disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
WO-2023089594-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2023-05-25 — — WO disclosed
EP-4146248-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-03-15 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241178-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885XIAP 2144/4885KMT2A 1516/4885
US-12622948-B2 GLP-1/GIP dual agonists GLP1R, GIPR, NPY4R GRB2 1289/4885XIAP 4385/4885KMT2A 766/4885
US-20240424063-A1 LONG ACTING GLP-1/GIP DUAL AGONISTS GLP1R, GIPR, GPR119 GRB2 524/4885XIAP 2144/4885KMT2A 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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