SCHEMBL29468837

SCHEMBL29468837

CC(C)(C)OC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.41
▸ DPP4 P27487 8/20 0.40
▸ DPP8 Q6V1X1 3/20 0.40
▸ FAP Q12884 1/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ DPP7 Q9UHL4 1/20 0.40
▸ ITGB1 P05556 1/20 0.39
▸ ITGA4 P13612 1/20 0.39
▸ GRB2 P62993 1/20 0.38
▸ CMA1 P23946 2/20 0.36
▸ ANPEP P15144 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30972553 0.98 KMT2A (0.42) KMT2ADPP4DPP8FAPDPP9
SCHEMBL30852867 0.91 CAPN1 (0.41) DPP4DPP8FAPDPP9DPP7
SCHEMBL29468849 0.87 REN (0.45) GRB2
SCHEMBL29397226 0.85 DPP4 (0.44) KMT2ADPP4DPP8FAPDPP9
SCHEMBL29397117 0.83 DPP4 (0.46) KMT2ADPP4DPP8FAPDPP9
SCHEMBL29468902 0.83 GRB2 (0.47) KMT2AITGB1ITGA4GRB2CMA1
SCHEMBL30096897 0.83 MEN1 (0.45) KMT2ADPP7MEN1
SCHEMBL30574235 0.82 DPP4 (0.42) KMT2ADPP4DPP8FAPDPP9
SCHEMBL30051232 0.82 KMT2A (0.51) KMT2ADPP4DPP8FAPDPP9
SCHEMBL29408003 0.82 DPP4 (0.45) KMT2ADPP4DPP8FAPDPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724471-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP disclosed
WO-2024252366-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO disclosed
EP-4204440-A1 GLP-1/GIP DUAL AGONISTS Sun Pharmaceutical Industries Limited (IN) 2023-07-05 — — EP disclosed
WO-2022079639-A1 GLP-1/GIP DUAL AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2022-04-21 — — WO disclosed
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