SCHEMBL2946900

SCHEMBL2946900

C=C[Si](CC(C)C)(OC(C)=O)OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202766 0.77 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL1493144 0.75 USP2 (0.31) ALDH1A1
SCHEMBL4951097 0.73 TSHR (0.31) TSHRALDH1A1
SCHEMBL13089367 0.72 HSD17B10 (0.30) TDP1
SCHEMBL128114 0.72 TSHR (0.32) TSHR
SCHEMBL475931 0.72 TSHR (0.36) TSHRALDH1A1TDP1
SCHEMBL2149328 0.72 TSHR (0.36) TSHRALDH1A1TDP1
SCHEMBL6054113 0.72 TSHR (0.36) TSHRALDH1A1TDP1
SCHEMBL4950952 0.71 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL476108 0.70 TSHR (0.35) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754331-B2 Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it KURARAY CO., LTD. (JP) 2010-07-13 US disclosed
US-20090274917-A1 ETHYLENE-VINYL ALCOHOL COPOLYMER COMPOSITION, AND POWDERY COATING COMPOSITION COMPRISING IT KURARAY CO. LTD (JP) 2009-11-05 US disclosed
US-20080274627-A1 SILICON-CONTAINING FILM, FORMING MATERIAL, MAKING METHOD, AND SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-11-06 US disclosed
EP-1291402-B1 Ethylene-vinyl alcohol copolymer composition, and powder coating composition comprising IT KURARAY CO (JP) 2007-06-13 EP disclosed
US-20060121270-A1 Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it KURARAY CO. LTD. (JP) 2006-06-08 US disclosed
US-20050081754-A1 Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it KURARAY CO. LTD, (JP) 2005-04-21 US disclosed
US-20030096101-A1 Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it KURARAY CO. LTD. (JP) 2003-05-22 US disclosed
EP-1291402-A1 Ethylene-vinyl alcohol copolymer composition, and powder coating composition comprising IT KURARAY CO., LTD. (JP) 2003-03-12 EP disclosed
EP-0146138-B1 MELT MOLDING MATERIAL KURARAY CO., LTD. (JP) 1988-12-28 EP disclosed
EP-0146138-A2 Melt molding material KURARAY CO., LTD. (JP) 1985-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274627-A1 SILICON-CONTAINING FILM, FORMING MATERIAL, MAKING METHOD, AND SEMICONDUCTOR DEVICE SIK1, SIK3, SIK2 TSHR 4806/4885ALDH1A1 3812/4885TDP1 4076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.