Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951097 | 0.88 | TSHR (0.31) | ALDH1A1TSHRHPGD | |
| SCHEMBL11358941 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRHPGDZDHHC20ZDHHC2 | |
| SCHEMBL12898552 | 0.80 | — | — | |
| SCHEMBL202766 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL3447698 | 0.74 | — | — | |
| SCHEMBL10911253 | 0.74 | LMNA (0.45) | ALDH1A1TSHRCES1 | |
| SCHEMBL1493144 | 0.74 | USP2 (0.31) | ALDH1A1 | |
| SCHEMBL475932 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRFAAHCES1 | |
| SCHEMBL703790 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRFAAHCES1 | |
| SCHEMBL1066665 | 0.73 | TSHR (0.35) | ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274627-A1 | SILICON-CONTAINING FILM, FORMING MATERIAL, MAKING METHOD, AND SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274627-A1 | SILICON-CONTAINING FILM, FORMING MATERIAL, MAKING METHOD, AND SEMICONDUCTOR DEVICE | SIK1, SIK3, SIK2 | ALDH1A1 3812/4885TSHR 4806/4885HPGD 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.