SCHEMBL2946940

SCHEMBL2946940

C=CCc1cc[c]c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
MAP4K4 O95819 1/20 0.34
RET P07949 1/20 0.34
IGF1R P08069 1/20 0.34
MET P08581 1/20 0.34
PIM1 P11309 1/20 0.34
LTK P29376 1/20 0.34
KDR P35968 1/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
CDK8 P49336 1/20 0.34
CLK2 P49760 1/20 0.34
CDK9 P50750 1/20 0.34
CDK5 Q00535 1/20 0.34
ACVR1 Q04771 1/20 0.34
PTK2 Q05397 1/20 0.34
MAP4K2 Q12851 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19856499 0.87 GABRA1 (0.42) GABRA1GABRB2AURKADAPK3MAP4K4
SCHEMBL293727 0.79
SCHEMBL293726 0.79
SCHEMBL7746016 0.79
SCHEMBL2305673 0.77 TSHR (0.32) GABRA1GABRB2AURKADAPK3MAP4K4
SCHEMBL13718969 0.76 CYP2A6 (0.36)
SCHEMBL5831736 0.75 GABRA1 (0.45) GABRA1GABRB2AURKADAPK3MAP4K4
SCHEMBL8382670 0.75 IDO1 (0.35)
SCHEMBL3477677 0.75 L3MBTL1 (0.33) KMT2A
SCHEMBL663537 0.75 GABRA1 (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675824-B1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS WURSTER SIEGFRIED (FI) 2010-09-29 EP claimed
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US claimed
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists OY JUVANTIA PHARMA LTD (FI) 2007-06-07 US claimed
JP-2007507473-A 2007-03-29 JP claimed
EP-1675824-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS Oy Juvantia Pharma Ltd (FI) 2006-07-05 EP claimed
WO-2005033068-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 WO claimed
WO-2005033069-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 WO claimed
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
US-20200148875-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2020-05-14 US disclosed
EP-3373051-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-11 EP disclosed
EP-3367144-B1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-04 EP disclosed
EP-3617758-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Corporation (JP) 2020-03-04 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3127929-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE FLUORINATED SILICONE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2017-02-08 EP disclosed
US-20170023704-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE FLUORINE-CONTAINING SILICONE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-01-26 US disclosed
EP-2029142-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION Choongwae Pharma Corporation (KR) 2009-03-04 EP disclosed
WO-2007139346-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2007-12-06 WO disclosed
EP-0428902-B1 Silver halide color photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
EP-0428902-A1 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists SSTR4, SSTR1, SSTR3 GABRA1 131/4885GABRB2 188/4885AURKA 2888/4885
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 GABRA1 131/4885GABRB2 188/4885AURKA 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.