Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30703497 | 0.83 | KDM4C (0.47) | ALDH1A1KDM4EL3MBTL1KDM4CADORA2A | |
| SCHEMBL305696 | 0.82 | CFTR (0.53) | ALDH1A1KDM4ECFTRGLRA3GLRB | |
| SCHEMBL2712692 | 0.81 | TDP1 (0.44) | ALDH1A1KDM4ECFTRL3MBTL1CYP11B2 | |
| SCHEMBL3713397 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL16463175 | 0.76 | CYP46A1 (0.58) | ALDH1A1KDM4EGLACFTRGLRA3 | |
| SCHEMBL29469507 | 0.75 | CFTR (0.52) | ALDH1A1KDM4EGAACFTRGLRA3 | |
| SCHEMBL16114117 | 0.75 | CFTR (0.55) | CFTRGLRA3GLRBCYP46A1TUBB4A | |
| SCHEMBL8348277 | 0.75 | CFTR (0.58) | ALDH1A1KDM4EGLAGAACFTR | |
| SCHEMBL29469470 | 0.74 | CFTR (0.45) | ALDH1A1KDM4EGLAGAACFTR | |
| SCHEMBL29479857 | 0.72 | L3MBTL1 (0.50) | ALDH1A1KDM4ECFTRGLRA3GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206443-B | Aromatic or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114206443-A | Aromatic ring or heteroaromatic ring derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |