Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 19/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313897 | 1.00 | ACACB (0.38) | ACACBBCHEACHE | |
| SCHEMBL17811813 | 0.84 | ACACB (0.39) | ACACBBCHEACHE | |
| SCHEMBL17811838 | 0.83 | ACACB (0.41) | ACACB | |
| SCHEMBL13091261 | 0.82 | ACACB (0.41) | ACACBBCHEACHE | |
| SCHEMBL20820450 | 0.81 | FFAR4 (0.37) | ACACB | |
| SCHEMBL24314212 | 0.80 | ACACB (0.39) | ACACB | |
| SCHEMBL24314292 | 0.80 | ACACB (0.37) | ACACB | |
| SCHEMBL24313901 | 0.80 | DHFR (0.44) | ACACBBCHEACHE | |
| SCHEMBL22587894 | 0.78 | ALDH1A1 (0.41) | ACACB | |
| SCHEMBL24314213 | 0.78 | ALDH1A1 (0.41) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4229045-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |