Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333740 | 1.00 | TP53 (0.37) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29469629 | 0.91 | ALDH1A1 (0.39) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29469645 | 0.91 | TP53 (0.36) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24334384 | 0.91 | ALDH1A1 (0.39) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24334282 | 0.91 | TP53 (0.36) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24334385 | 0.91 | ALDH1A1 (0.39) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29469652 | 0.90 | RORC (0.36) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24333707 | 0.90 | RORC (0.36) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24334420 | 0.88 | ALDH1A1 (0.36) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29469703 | 0.88 | ALDH1A1 (0.36) | TP53ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | The Broad Institute, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |