SCHEMBL29470182

SCHEMBL29470182

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.57
▸ ERAP2 Q6P179 2/20 0.56
▸ MEN1 O00255 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ ECE1 P42892 11/20 0.54
▸ MAGI3 Q5TCQ9 1/20 0.53
▸ CTSC P53634 1/20 0.53
▸ IL1RN P18510 1/20 0.52
▸ ERAP1 Q9NZ08 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379665 0.94 CTSC (0.61) ACEERAP2MEN1KMT2AECE1
SCHEMBL30052714 0.94 ACE (0.64) ACEERAP2MEN1KMT2AECE1
SCHEMBL29379360 0.91 CTSC (0.64) ACEERAP2MEN1KMT2AECE1
SCHEMBL30051469 0.90 ACE (0.61) ACEERAP2MEN1KMT2AECE1
SCHEMBL17534383 0.90 ERAP2 (0.60) ACEERAP2MEN1KMT2AECE1
SCHEMBL17534378 0.90 ERAP2 (0.60) ACEERAP2MEN1KMT2AECE1
SCHEMBL29470185 0.89 ACE (0.61) ACEERAP2MEN1KMT2AECE1
SCHEMBL30452439 0.88 ACE (0.62) ACEERAP2ECE1MAGI3
SCHEMBL30051361 0.87 ACE (0.62) ACEERAP2MEN1KMT2AECE1
SCHEMBL30051511 0.86 CTSC (0.64) ACEERAP2MEN1KMT2AECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells PURDUE RESEARCH FOUNDATION (US) 2025-10-21 — — US disclosed
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS PURDUE RESEARCH FOUNDATION (US) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220120756-A1 METHOD AND COMPOSITION MATTER FOR IMMUNOPROTEASOME-MEDIATED DELIVERY INTO LIVING CELLS EXOSC5, PSMG3, EXOSC4 ACE 563/4885ERAP2 105/4885MEN1 2351/4885
US-12449422-B2 Method and composition matter for immunoproteasome-mediated delivery into living cells EXOSC5, PSMG3, EXOSC4 ACE 563/4885ERAP2 105/4885MEN1 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback