SCHEMBL29470232

SCHEMBL29470232

Fc1cccc(-c2cccc(-c3cccc(F)c3)n2)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 2/20 0.58
MAPT P10636 1/20 0.58
IDO1 P14902 2/20 0.55
KMO O15229 2/20 0.54
RAB9A P51151 1/20 0.54
MAP4K4 O95819 4/20 0.53
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
ESR2 Q92731 1/20 0.48
GRM5 P41594 1/20 0.47
ALDH1A1 P00352 1/20 0.46
HPGDS O60760 1/20 0.46
MAOB P27338 1/20 0.46
NOTUM Q6P988 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4547006 0.86 KDM4E (0.55) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL7392830 0.86 KDM4E (0.50) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL3923558 0.86 ASIC3 (0.62) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL7392834 0.86 CCR1 (0.56) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL17174137 0.81 MAP4K4 (0.58) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL29897575 0.81 KMO (0.48) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL20700571 0.81 KDM4E (0.46) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL20878875 0.81 MAP4K4 (0.47) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL29897526 0.81 KDM4E (0.46) MEN1KMT2AKDM4EMAPTIDO1
SCHEMBL17595532 0.81 KMO (0.48) MEN1KMT2AKDM4EMAPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163381-A Method for synthesizing (2, 6-diphenylpyridine-3, 5-diacyl) bis (benzophenone) and derivatives thereof 温州医科大学 2022-03-11 CN disclosed