Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270009 | 1.00 | CES2 (0.44) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL3753980 | 1.00 | CES2 (0.44) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL4210961 | 1.00 | CES2 (0.44) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL28869538 | 1.00 | CES2 (0.44) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL28420309 | 0.98 | CES2 (0.42) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL15809341 | 0.96 | CES2 (0.41) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL25509010 | 0.96 | KDM5A (0.44) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL8386144 | 0.94 | CES2 (0.39) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL1777056 | 0.91 | CA1 (0.46) | CES2CES1SOAT1MEN1FAAH | |
| SCHEMBL8383111 | 0.89 | KDM5A (0.41) | CES2CES1SOAT1MEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787127-A | Ionizable lipids and nanoparticle compositions thereof | 世代生物公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114127044-A | Ionizable amine lipids and lipid nanoparticles | 英特利亚治疗股份有限公司 | 2022-03-01 | — | — | CN | disclosed |