SCHEMBL3753980

SCHEMBL3753980

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
SOAT1 P35610 2/20 0.44
MEN1 O00255 1/20 0.44
FAAH O00519 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM5A P29375 2/20 0.42
PHF8 Q9UPP1 2/20 0.42
KDM4C Q9H3R0 1/20 0.42
DNM1 Q05193 4/20 0.41
KDM4E B2RXH2 2/20 0.40
ICMT O60725 1/20 0.39
ALB P02768 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13270009 1.00 CES2 (0.44) CES2CES1SOAT1MEN1FAAH
SCHEMBL29470959 1.00 CES2 (0.44) CES2CES1SOAT1MEN1FAAH
SCHEMBL4210961 1.00 CES2 (0.44) CES2CES1SOAT1MEN1FAAH
SCHEMBL28869538 1.00 CES2 (0.44) CES2CES1SOAT1MEN1FAAH
SCHEMBL28420309 0.98 CES2 (0.42) CES2CES1SOAT1MEN1FAAH
SCHEMBL15809341 0.96 CES2 (0.41) CES2CES1SOAT1MEN1FAAH
SCHEMBL25509010 0.96 KDM5A (0.44) CES2CES1SOAT1MEN1FAAH
SCHEMBL8386144 0.94 CES2 (0.39) CES2CES1SOAT1MEN1FAAH
SCHEMBL1777056 0.91 CA1 (0.46) CES2CES1SOAT1MEN1FAAH
SCHEMBL8383111 0.89 KDM5A (0.41) CES2CES1SOAT1MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368264-B Compounds, liposomes and uses thereof 北京理工大学 2025-03-07 CN claimed
CN-118252815-A Cell membrane coated nucleic acid lipid composite nanoparticle and preparation method and application thereof 杭州纽安津生物科技有限公司 2024-06-28 CN claimed
CN-114099699-B Nanometer delivery system and preparation method and application thereof 华南理工大学 2024-03-19 CN claimed
CN-112791192-B Inflammatory cell targeted melittin liposome nano preparation and preparation method and application thereof 上海交通大学 2023-04-07 CN claimed
CN-115671045-A Non-liver-targeting nucleic acid nano preparation and preparation method and application thereof 华南理工大学 2023-02-03 CN claimed
CN-115531617-A Stomach fistulization catheter coated with lipid polysaccharide compound 上海市徐汇区大华医院 2022-12-30 CN claimed
CN-115414536-A Gene elution balloon and preparation method and application thereof 苏州中天医疗器械科技有限公司 2022-12-02 CN claimed
CN-115368264-A Compound, liposome and application thereof 北京理工大学 2022-11-22 CN claimed
CN-111701029-B Up-conversion bionic complex, preparation method and application of weak ultraviolet conversion 济南康硕生物技术有限公司 2022-08-16 CN claimed
CN-114540416-A Expression vector, lipid nanoparticle, antitumor drug, preparation method and application thereof 上海交通大学 2022-05-27 CN claimed
CN-114053225-A High-efficiency low-toxicity and good-stability cationic liposome for gene delivery and application thereof 浙江大学 2022-02-18 CN claimed
CN-112791192-A Inflammatory cell targeted melittin liposome nano preparation and preparation method and application thereof 上海交通大学 2021-05-14 CN claimed
CN-115368264-B Compounds, liposomes and uses thereof 北京理工大学 2025-03-07 CN disclosed
CN-118284692-A Gene editing of PCSK9 or ANGPTL3 and compositions and methods of using same for treating diseases 维乎医疗有限公司 2024-07-02 CN disclosed
CN-118108847-A MRNA mediated immune method 诺华股份有限公司 2024-05-31 CN disclosed
CN-115304756-B Five-membered lipid nanoparticle as well as preparation method and application thereof 上海科技大学 2023-05-09 CN disclosed
CN-113855634-A Polypeptide-modified liposome, mRNA (messenger ribonucleic acid) delivery system and dendritic cell vaccine 四川大学 2021-12-31 CN disclosed
CN-113332264-A Composition containing sophora flavescens extract for pulmonary administration and preparation method and application thereof 贵州医科大学 2021-09-03 CN disclosed
CN-109562153-A mRNA mediated immunization methods 诺华股份有限公司 2019-04-02 CN disclosed
US-20100297023-A1 Lipid IMUTHES LIMITED UNIVERSITY OF THE WITWATERSRAND 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100297023-A1 Lipid NR1H2, NR1H3, NR1H4 CES2 871/4885CES1 394/4885SOAT1 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.