Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470957 | 0.90 | OPRM1 (0.36) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL2607180 | 0.85 | OPRM1 (0.54) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| Iodide SCHEMBL30309825 | 0.84 | OPRM1 (0.53) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL17286018 | 0.81 | SMN1; SMN2 (0.50) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL1439148 | 0.81 | ALDH1A1 (0.38) | SLC22A1KCNH2SCN1ASCN2ASCN3A | |
| SCHEMBL1439277 | 0.79 | CYP3A4 (0.40) | KCNH2SCN1ASCN2ASCN3ACHRM5 | |
| SCHEMBL17284634 | 0.78 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL24763400 | 0.77 | OPRM1 (0.37) | OPRM1SLC22A1SLC6A4ADRA1AOPRD1 | |
| SCHEMBL12881565 | 0.77 | POLB (0.37) | CHRM1ALDH1A1 | |
| SCHEMBL18819444 | 0.75 | ALDH1A1 (0.38) | KCNH2CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127044-A | Ionizable amine lipids and lipid nanoparticles | 英特利亚治疗股份有限公司 | 2022-03-01 | — | — | CN | disclosed |